Genomic and phenotypic insights from an atlas of genetic effects on DNA methylation
- Min, Josine L., Hemani, Gibran, Bretherick, Andrew D., Pennell, Craig E., Richardson, Tom G., Klughammer, Johanna, Iotchkova, Valentina, Sharp, Gemma, Al Khleifat, Ahmad, Shatunov, Aleksey, Iacoangeli, Alfredo, McArdle, Wendy L., Ho, Karen M., Hannon, Ellis, Kumar, Ashish, Söderhäll, C, Soriano-Tárraga, C, Giralt-Steinhauer, E, Kazmi, N, Mason, D, McRae, AF, Corcoran, DL, Sugden, K, Kasela, S, Dekkers, Koen F., Cardona, A, Day, FR, Cugliari, G, Viberti, C, Guarrera, S, Lerro, M, Gupta, R, Bollepalli, S, Mandaviya, P, Zeng, Y, Castillo-Fernandez, Juan, Clarke, TK, Walker, RM, Schmoll, V, Czamara, D, Ruiz-Arenas, C, Rezwan, FI, Marioni, RE, Lin, T, Awaloff, Y, Germain, M, Luijk, Rene, Aïssi, D, Zwamborn, R, van Eijk, K, Dekker, A, van Dongen, J, Hottenga, JJ, Willemsen, G, Xu, CJ, Barturen, G, Català-Moll, F, Carnero-Montoro, Elena, Kerick, M, Wang, Carol, Melton, P, Elliott, HR, Shin, J, Bernard, M, Yet, I, Smart, M, Gorrie-Stone, T, Shaw, C, Lawson, Daniel J., Al Chalabi, A, Ring, SM, Pershagen, G, Melén, E, Jiménez-Conde, J, Roquer, J, Lawlor, DA, Wright, J, Martin, NG, Montgomery, GW, Burrows, Kimberley, Moffitt, TE, Poulton, R, Esko, T, Milani, L, Metspalu, A, Perry, JRB, Ong, KK, Wareham, NJ, Matullo, G, Sacerdote, C, Suderman, Matthew, Panico, S, Caspi, A, Arseneault, L, Gagnon, F, Ollikainen, M, Kaprio, J, Felix, JF, Rivadeneira, F, Tiemeier, H, van IJzendoorn, MH
- Creator: Min, Josine L. , Hemani, Gibran , Bretherick, Andrew D. , Pennell, Craig E. , Richardson, Tom G. , Klughammer, Johanna , Iotchkova, Valentina , Sharp, Gemma , Al Khleifat, Ahmad , Shatunov, Aleksey , Iacoangeli, Alfredo , McArdle, Wendy L. , Ho, Karen M. , Hannon, Ellis , Kumar, Ashish , Söderhäll, C , Soriano-Tárraga, C , Giralt-Steinhauer, E , Kazmi, N , Mason, D , McRae, AF , Corcoran, DL , Sugden, K , Kasela, S , Dekkers, Koen F. , Cardona, A , Day, FR , Cugliari, G , Viberti, C , Guarrera, S , Lerro, M , Gupta, R , Bollepalli, S , Mandaviya, P , Zeng, Y , Castillo-Fernandez, Juan , Clarke, TK , Walker, RM , Schmoll, V , Czamara, D , Ruiz-Arenas, C , Rezwan, FI , Marioni, RE , Lin, T , Awaloff, Y , Germain, M , Luijk, Rene , Aïssi, D , Zwamborn, R , van Eijk, K , Dekker, A , van Dongen, J , Hottenga, JJ , Willemsen, G , Xu, CJ , Barturen, G , Català-Moll, F , Carnero-Montoro, Elena , Kerick, M , Wang, Carol , Melton, P , Elliott, HR , Shin, J , Bernard, M , Yet, I , Smart, M , Gorrie-Stone, T , Shaw, C , Lawson, Daniel J. , Al Chalabi, A , Ring, SM , Pershagen, G , Melén, E , Jiménez-Conde, J , Roquer, J , Lawlor, DA , Wright, J , Martin, NG , Montgomery, GW , Burrows, Kimberley , Moffitt, TE , Poulton, R , Esko, T , Milani, L , Metspalu, A , Perry, JRB , Ong, KK , Wareham, NJ , Matullo, G , Sacerdote, C , Suderman, Matthew , Panico, S , Caspi, A , Arseneault, L , Gagnon, F , Ollikainen, M , Kaprio, J , Felix, JF , Rivadeneira, F , Tiemeier, H , van IJzendoorn, MH
- Resource Type: journal article
- Date: 2021
Multiple sclerosis genomic map implicates peripheral immune cells and microglia in susceptibility
- Patsopoulos, Nikolaos A., Baranzini, Sergio E., McCabe, Cristin, Thorpe, J, Bradshaw, E, Caillier, SJ, Calabresi, P, Cree, BAC, Cross, A, Davis, M, de Bakker, PWI, Delgado, S, Dembele, M, Pers, Tune H., Edwards, K, Fitzgerald, K, Frohlich, IY, Gourraud, P-A, Haines, JL, Hakonarson, H, Kimbrough, D, Isobe, N, Konidari, I, Lathi, E, Brandes, Aaron, Lee, MH, Li, T, An, D, Zimmer, A, Madireddy, L, Manrique, CP, Mitrovic, M, Olah, M, Patrick, E, Pericak-Vance, MA, White, Charles, Piccio, L, Schaefer, C, Weiner, H, Lage, K, Scott, RJ, Lechner-Scott, J, Leal, R, Moscato, P, Booth, DR, Stewart, GJ, Keenan, Brendan, Vucic, S, Pame, G, BamettO, M, Mason, D, GriffithS, L, Broadley, S, Tajouri, L, Baxter, A, Slee, M, Taylor, BV, Cimpean, Maria, Charlesworth, J, Kilpatrick, TJ, Rubio, J, Jokubaitis, V, Wiley, J, Butzkueven, H, Leslie, S, Motyer, A, Stankovich, J, Carroll, WM, Winn, Phoebe, Kermode, AG, Edrin, M, Barclay, M, Peyrin-Biroulet, L, Chamaillard, M, Colombe, J-F, Cottone, M, Croft, A, D'Inca, R, Halfvarson, J, Panteliadis, Ioannis-Pavlos, Hanigan, K, Henderson, P, Hugot, J-P, Karban, A, Kennedy, NA, Khan, MA, Lemann, M, Levine, A, Massey, D, Milla, M, Robbins, Allison, Motoey, GW, Ng, SME, Oikonomnou, J, Peeters, H, Proctor, DD, Rahier, J-F, Roberts, R, Rutgeerts, P, Seibold, F, Stronati, L, Andlauer, Till F. M., Taylor, KM, Torkvist, L, Ublick, K, Van Limbergen, J, Van Gossum, A, Vatn, MH, Zhang, H, Zhang, W, Donnelly, P, Barroso, I, Santaniello, Adam, Zarzycki, Onigiusz, Blackwe, JM, Bramon, E, Brown, MA, Casas, JP, Corvin, A, Deloukas, P, Duncanson, A, Jankowski, J, Markus, HS, Mathew, CG, Dubois, B, Palmer, CNA, Plomin, R, Rautanen, A, Sawcer, SJ, Trembath, RC, Viswanathan, AC, Wood, NW, Spencer, CCA, Band, G, Bellenguez, C, Goris, A, Freeman, C, Hellenthal, G, Giannoulatou, E, Pirinen, M, Pearson, R, Strange, A, Sul, Z, Vukcevic, DA, Langford, C, Sondergaard, HB, Hunt, SE, Edkins, S, Gwilliam, R, Blackburn, H, Bumpstead, SJ, Dronov, S, Gillman, M, Gray, E, Hammond, N, Jayakumar, A, Sellebjerg, F, McCann, OT, Liddle, J, Potter, SC, Ravindrarajah, R, Ricketts, M, Waller, M, Weston, P, Widaa, S, Whittaker, P, Sorensen, PS, Compston, A, Hafler, D, Harbo, HF, Hauser, SL, Ullum, H, Stewart, G, D'Alfonso, S, Hadjigeorgiou, G, Taylor, B, Barcellos, LF, Booth, D, Hintzen, R, Kockum, I, Martinelli-Boneschi, F, McCauley, JL, Thorner, LW, Oksenberg, JR, Oturai, A, Sawcer, S, Ivinson, AJ, Olsson, T, De Jager, PL, Saarela, J., Cournu-Rebeix, I, Shoostari, Parisa, Damotte, V, Fontaine, B, Guillot-Noel, L, Lathrop, M, Vukusic, S, Berthele, A, Pongratz, V, Gasperi, C, Graetz, C, Cotsapas, Chris, Grummel, V, Hemmer, B, Hoshi, M, Knier, B, Korn, T, Lill, CM, Luessi, F, Muehlau, M, Zipp, F, Dardiotis, E, Wong, Garrett, Agliardi, C, Amoroso, A, Barizzone, N, Benedetti, MD, Bernardinelli, L, Cavalla, P, Clarelli, F, Comi, G, Cusi, D, Esposito, F, Beecham, Ashley H., Ferre, L, Galimberti, D, Guaschino, C, Leone, MA, Martinelli, V, Moiola, L, Salvetti, M, Sorosina, M, Vecchio, D, Zauli, A, James, Tojo, Santoro, S, Mancini, N, Zuccala, M, Mescheriakova, J, van Duijn, C, Bos, SD, Celius, EG, Spurkland, A, Comabella, M, Montalban, X, Replogle, Joseph, Alfredsson, L, Bomfim, IL, Gomez-Cabrero, D, Hillert, J, Jagodic, M, Linden, M, Piehl, F, Jelcic, I, Martin, R, Sospedra, M, Vlachos, Ioannis S., Baker, A, Ban, M, Hawkins, C, Hysi, P, Kalra, S, Karpe, F, Khadake, J, Lachance, G, Molyneux, P, Neville, M
- Creator: Patsopoulos, Nikolaos A. , Baranzini, Sergio E. , McCabe, Cristin , Thorpe, J , Bradshaw, E , Caillier, SJ , Calabresi, P , Cree, BAC , Cross, A , Davis, M , de Bakker, PWI , Delgado, S , Dembele, M , Pers, Tune H. , Edwards, K , Fitzgerald, K , Frohlich, IY , Gourraud, P-A , Haines, JL , Hakonarson, H , Kimbrough, D , Isobe, N , Konidari, I , Lathi, E , Brandes, Aaron , Lee, MH , Li, T , An, D , Zimmer, A , Madireddy, L , Manrique, CP , Mitrovic, M , Olah, M , Patrick, E , Pericak-Vance, MA , White, Charles , Piccio, L , Schaefer, C , Weiner, H , Lage, K , Scott, RJ , Lechner-Scott, J , Leal, R , Moscato, P , Booth, DR , Stewart, GJ , Keenan, Brendan , Vucic, S , Pame, G , BamettO, M , Mason, D , GriffithS, L , Broadley, S , Tajouri, L , Baxter, A , Slee, M , Taylor, BV , Cimpean, Maria , Charlesworth, J , Kilpatrick, TJ , Rubio, J , Jokubaitis, V , Wiley, J , Butzkueven, H , Leslie, S , Motyer, A , Stankovich, J , Carroll, WM , Winn, Phoebe , Kermode, AG , Edrin, M , Barclay, M , Peyrin-Biroulet, L , Chamaillard, M , Colombe, J-F , Cottone, M , Croft, A , D'Inca, R , Halfvarson, J , Panteliadis, Ioannis-Pavlos , Hanigan, K , Henderson, P , Hugot, J-P , Karban, A , Kennedy, NA , Khan, MA , Lemann, M , Levine, A , Massey, D , Milla, M , Robbins, Allison , Motoey, GW , Ng, SME , Oikonomnou, J , Peeters, H , Proctor, DD , Rahier, J-F , Roberts, R , Rutgeerts, P , Seibold, F , Stronati, L , Andlauer, Till F. M. , Taylor, KM , Torkvist, L , Ublick, K , Van Limbergen, J , Van Gossum, A , Vatn, MH , Zhang, H , Zhang, W , Donnelly, P , Barroso, I , Santaniello, Adam , Zarzycki, Onigiusz , Blackwe, JM , Bramon, E , Brown, MA , Casas, JP , Corvin, A , Deloukas, P , Duncanson, A , Jankowski, J , Markus, HS , Mathew, CG , Dubois, B , Palmer, CNA , Plomin, R , Rautanen, A , Sawcer, SJ , Trembath, RC , Viswanathan, AC , Wood, NW , Spencer, CCA , Band, G , Bellenguez, C , Goris, A , Freeman, C , Hellenthal, G , Giannoulatou, E , Pirinen, M , Pearson, R , Strange, A , Sul, Z , Vukcevic, DA , Langford, C , Sondergaard, HB , Hunt, SE , Edkins, S , Gwilliam, R , Blackburn, H , Bumpstead, SJ , Dronov, S , Gillman, M , Gray, E , Hammond, N , Jayakumar, A , Sellebjerg, F , McCann, OT , Liddle, J , Potter, SC , Ravindrarajah, R , Ricketts, M , Waller, M , Weston, P , Widaa, S , Whittaker, P , Sorensen, PS , Compston, A , Hafler, D , Harbo, HF , Hauser, SL , Ullum, H , Stewart, G , D'Alfonso, S , Hadjigeorgiou, G , Taylor, B , Barcellos, LF , Booth, D , Hintzen, R , Kockum, I , Martinelli-Boneschi, F , McCauley, JL , Thorner, LW , Oksenberg, JR , Oturai, A , Sawcer, S , Ivinson, AJ , Olsson, T , De Jager, PL , Saarela, J. , Cournu-Rebeix, I , Shoostari, Parisa , Damotte, V , Fontaine, B , Guillot-Noel, L , Lathrop, M , Vukusic, S , Berthele, A , Pongratz, V , Gasperi, C , Graetz, C , Cotsapas, Chris , Grummel, V , Hemmer, B , Hoshi, M , Knier, B , Korn, T , Lill, CM , Luessi, F , Muehlau, M , Zipp, F , Dardiotis, E , Wong, Garrett , Agliardi, C , Amoroso, A , Barizzone, N , Benedetti, MD , Bernardinelli, L , Cavalla, P , Clarelli, F , Comi, G , Cusi, D , Esposito, F , Beecham, Ashley H. , Ferre, L , Galimberti, D , Guaschino, C , Leone, MA , Martinelli, V , Moiola, L , Salvetti, M , Sorosina, M , Vecchio, D , Zauli, A , James, Tojo , Santoro, S , Mancini, N , Zuccala, M , Mescheriakova, J , van Duijn, C , Bos, SD , Celius, EG , Spurkland, A , Comabella, M , Montalban, X , Replogle, Joseph , Alfredsson, L , Bomfim, IL , Gomez-Cabrero, D , Hillert, J , Jagodic, M , Linden, M , Piehl, F , Jelcic, I , Martin, R , Sospedra, M , Vlachos, Ioannis S. , Baker, A , Ban, M , Hawkins, C , Hysi, P , Kalra, S , Karpe, F , Khadake, J , Lachance, G , Molyneux, P , Neville, M
- Resource Type: journal article
- Date: 2019
Phenome-wide association analysis of LDL-cholesterol lowering genetic variants in PCSK9
- Schmidt, Amand F., Holmes, Michael V., Preiss, David, Swerdlow, Daniel I., Denaxas, Spiros, Fatemifar, Ghazaleh, Faraway, Rupert, Finan, Chris, Valentine, Dennis, Fairhurst-Hunter, Zammy, Hartwig, Fernando Pires, Horta, Bernardo Lessa, Hypponen, Elina, Power, Christine, Moldovan, Max, van Iperen, Erik, Hovingh, Kees, Demuth, Ilja, Norman, Kristina, Steinhagen-Thiessen, Elisabeth, Hancock, Stephen, Attia, John, Holliday, Elizabeth, Scott, Rodney, Teumer, A, Baumeister, S, Doerr, M, Lerch, MM, Voelker, U, Voelzke, H, Ward, J, Pell, JP, Meade, T, Christophersen, IE, Maitland-van der Zee, AH, Baranova, EV, Young, R, Ford, I, Campbell, A, Padmanabhan, S, Bots, ML, Grobbee, DE, Froguel, P, Thuillier, D, Roussel, R, Bonnefond, A, Cariou, B, Smart, M, Bao, Y, Kumari, M, Mahajan, A, Hopewell, JC, Seshadri, S, Dale, C, Costa, RPE, Ridker, PM, Chasman, DI, Reiner, AP, Ritchie, MD, Lange, LA, Cornish, AJ, Dobbins, SE, Hemminki, K, Kinnersley, B, Sanson, M, Labreche, K, Simon, M, Bondy, M, Law, P, Speedy, H, Allan, J, Li, N, Went, M, Weinhold, N, Morgan, G, Sonneveld, P, Nilsson, B, Goldschmidt, H, Sud, A, Engert, A, Hansson, M, Hemingway, H, Asselbergs, FW, Patel, RS, Keating, BJ, Sattar, N, Houlston, R, Casas, JP, Hingorani, AD, Demuth, Juri, Bertram, L, Lill, CM, Coassin, S, Willeit, J, Kiechl, S, Willeit, K, Mason, D, Wright, J, Morris, R, Wanamethee, G, Whincup, P, Ben-Shlomo, Y, McLachlan, S, Price, JF, Kivimaki, M, Welch, C, Sanchez-Galvez, A, Marques-Vidal, P, Nicolaides, A, Panayiotou, AG, Onland-Moret, NC, van der Schouw, YT, Matullo, G, Fiorito, G, Guarrera, S, Sacerdote, C, Wareham, NJ, Langenberg, C, Scott, RA, Luan, J, Bobak, M, Malyutina, S, Pajak, A, Kubinova, R, Tamosiunas, A, Pikhart, H, Grarup, N, Pedersen, O, Hansen, T, Linneberg, A, Jess, T, Cooper, J, Humphries, SE, Brilliant, M, Kitchner, T, Hakonarson, H, Carrell, DS, McCarty, CA, Lester, KH, Larson, EB, Crosslin, DR, de Andrade, M, Roden, DM, Denny, JC, Carty, C, Schofield, P, O'Donnell, M, Yusuf, S, Chong, M, Pare, G, van der Harst, P, Said, MA, Eppinga, RN, Verweij, N, Snieder, H, Christen, T, Mook-Kanamori, DO, Gustafsson, S, Lind, L, Ingelsson, E, Pazoki, R, Franco, O, Hofman, A, Uitterlinden, A, Dehghan, A
- Creator: Schmidt, Amand F. , Holmes, Michael V. , Preiss, David , Swerdlow, Daniel I. , Denaxas, Spiros , Fatemifar, Ghazaleh , Faraway, Rupert , Finan, Chris , Valentine, Dennis , Fairhurst-Hunter, Zammy , Hartwig, Fernando Pires , Horta, Bernardo Lessa , Hypponen, Elina , Power, Christine , Moldovan, Max , van Iperen, Erik , Hovingh, Kees , Demuth, Ilja , Norman, Kristina , Steinhagen-Thiessen, Elisabeth , Hancock, Stephen , Attia, John , Holliday, Elizabeth , Scott, Rodney , Teumer, A , Baumeister, S , Doerr, M , Lerch, MM , Voelker, U , Voelzke, H , Ward, J , Pell, JP , Meade, T , Christophersen, IE , Maitland-van der Zee, AH , Baranova, EV , Young, R , Ford, I , Campbell, A , Padmanabhan, S , Bots, ML , Grobbee, DE , Froguel, P , Thuillier, D , Roussel, R , Bonnefond, A , Cariou, B , Smart, M , Bao, Y , Kumari, M , Mahajan, A , Hopewell, JC , Seshadri, S , Dale, C , Costa, RPE , Ridker, PM , Chasman, DI , Reiner, AP , Ritchie, MD , Lange, LA , Cornish, AJ , Dobbins, SE , Hemminki, K , Kinnersley, B , Sanson, M , Labreche, K , Simon, M , Bondy, M , Law, P , Speedy, H , Allan, J , Li, N , Went, M , Weinhold, N , Morgan, G , Sonneveld, P , Nilsson, B , Goldschmidt, H , Sud, A , Engert, A , Hansson, M , Hemingway, H , Asselbergs, FW , Patel, RS , Keating, BJ , Sattar, N , Houlston, R , Casas, JP , Hingorani, AD , Demuth, Juri , Bertram, L , Lill, CM , Coassin, S , Willeit, J , Kiechl, S , Willeit, K , Mason, D , Wright, J , Morris, R , Wanamethee, G , Whincup, P , Ben-Shlomo, Y , McLachlan, S , Price, JF , Kivimaki, M , Welch, C , Sanchez-Galvez, A , Marques-Vidal, P , Nicolaides, A , Panayiotou, AG , Onland-Moret, NC , van der Schouw, YT , Matullo, G , Fiorito, G , Guarrera, S , Sacerdote, C , Wareham, NJ , Langenberg, C , Scott, RA , Luan, J , Bobak, M , Malyutina, S , Pajak, A , Kubinova, R , Tamosiunas, A , Pikhart, H , Grarup, N , Pedersen, O , Hansen, T , Linneberg, A , Jess, T , Cooper, J , Humphries, SE , Brilliant, M , Kitchner, T , Hakonarson, H , Carrell, DS , McCarty, CA , Lester, KH , Larson, EB , Crosslin, DR , de Andrade, M , Roden, DM , Denny, JC , Carty, C , Schofield, P , O'Donnell, M , Yusuf, S , Chong, M , Pare, G , van der Harst, P , Said, MA , Eppinga, RN , Verweij, N , Snieder, H , Christen, T , Mook-Kanamori, DO , Gustafsson, S , Lind, L , Ingelsson, E , Pazoki, R , Franco, O , Hofman, A , Uitterlinden, A , Dehghan, A
- Resource Type: journal article
- Date: 2019
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